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Disabled homolog 2

Summary

UniProt ID

O88797

Gene Symbol

Dab2
Doc2

Gene ID

79128

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: O88797
PubChem: O88797
The Human Metabolome Database: HMDBP14528
Re-Glyco: O88797

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Coated pit
Cytoplasm
Cytoplasmic vesicle
Developmental protein
Differentiation
Endocytosis
Phosphoprotein
Protein transport
Reference proteome
Wnt signaling pathway

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
cytoplasm
plasma membrane
intracellular membrane-bounded organelle
apical plasma membrane
clathrin-coated vesicle
perinuclear region of cytoplasm
clathrin-coated pit
clathrin coat of coated pit
clathrin-coated vesicle membrane
fibrillar center

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 45 in total

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GO Term
positive regulation of aldosterone secretion
in utero embryonic development
protein transport
myeloid cell differentiation
negative regulation of cell growth
positive regulation of cell migration
negative regulation of apoptotic process
positive regulation of cell adhesion
positive regulation of endocytosis
negative regulation of epithelial cell proliferation

Displaying **all 9** entries
GO Term
integrin binding
phosphatidylinositol-4,5-bisphosphate binding
clathrin binding
phosphatidylinositol binding
AP-2 adaptor complex binding
cargo receptor activity
SMAD binding
low-density lipoprotein particle receptor binding
clathrin adaptor activity

Annotation information from UniProt.

Sequence

MSNEVETSTTNGQPDQQAAPKAPSKKEKKKGSEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNNPTESRDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPESAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFHSLTSADQKKANPGSLSTPQSKGPLNGDTDYFGQQFDQISNRTGKQEAQGGPWPYPSSQTQQAVRTQNGVSEKEQNGFHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFASEPPGQMSPTGQPAVPQANFMDLFKTSAPAPMGSGPLVGLGTVPVTPPQAGPWTPVVFTPSTTVVPGAIISGQPSGFGQPLVFGTTPAVQVWNQPSSFATAASPPPPAVWCPTTSVAPNTWSSTSPLGNPFQSSNIFPPSTISTQSFPQPMMSSVLVTPPQPPPRNGPLKDTLSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPSSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQGVLSGTKSADNSLENPFSKGFSSTNPSVVSQPASSDAHRSPFGNPFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
506				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
Formation of annular gap junctions	Rattus norvegicus
Gap junction degradation	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5844	myocardial infarction	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements