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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Caspase-8
Summary
- UniProt ID
- O89110
- Gene Symbol
-
- Casp8
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Apoptosis
- Cytoplasm
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Thiol protease
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| response to ethanol |
| extrinsic apoptotic signaling pathway |
| extrinsic apoptotic signaling pathway via death domain receptors |
| pyroptosis |
| self proteolysis |
| positive regulation of extrinsic apoptotic signaling pathway |
Sequence
MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHISRWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLLEIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGREELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNYIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation by c-FLIP | Mus musculus |
| Regulation of NF-kappa B signaling | Mus musculus |
| Regulation of TNFR1 signaling | Mus musculus |
| Regulation of necroptotic cell death | Mus musculus |
| TRAIL signaling | Mus musculus |
| TRIF-mediated programmed cell death | Mus musculus |
