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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Interleukin-18 receptor accessory protein
Summary
- UniProt ID
- O95256
- Gene Symbol
-
- IL18RAP
- IL1R7
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O95256
- PubChem
- O95256
- The Human Metabolome Database
- HMDBP12409
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Hydrolase
- Immunoglobulin domain
- Inflammatory response
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| interleukin-18 receptor complex |
| plasma membrane |
| GO Term |
|---|
| NAD+ nucleotidase, cyclic ADP-ribose generating |
| NAD+ nucleosidase activity |
| coreceptor activity |
| interleukin-18 receptor activity |
Sequence
MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 | N-linked (GlcNAc...) asparagine |
|
||
| 119 | N-linked (GlcNAc...) asparagine |
|
||
| 152 | N-linked (GlcNAc...) asparagine |
|
||
| 345 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-18 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050657 | Bannayan-Riley-Ruvalcaba syndrome | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0110741 | type 1 diabetes mellitus 2 | |
| DOID:0110742 | type 1 diabetes mellitus 3 | |
| DOID:0110743 | type 1 diabetes mellitus 4 | |
| DOID:0110744 | type 1 diabetes mellitus 5 | |
| DOID:0110745 | type 1 diabetes mellitus 6 | |
| DOID:0110746 | type 1 diabetes mellitus 7 | |
| DOID:0110747 | type 1 diabetes mellitus 8 |
