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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GPI ethanolamine phosphate transferase 1
Summary
- UniProt ID
- O95427
- Gene Symbol
-
- PIGN
- MCD4
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- O95427
- PubChem
- O95427
- The Human Metabolome Database
- HMDBP07328
Annotation
- Keyword
-
- Disease variant
- Endoplasmic reticulum
- Epilepsy
- GPI-anchor biosynthesis
- Glycoprotein
- Reference proteome
- Transferase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| GPI anchor biosynthetic process |
| preassembly of GPI anchor in ER membrane |
| GO Term |
|---|
| endoplasmic reticulum membrane |
| cytosol |
| plasma membrane |
| membrane |
| GO Term |
|---|
| mannose-ethanolamine phosphotransferase activity |
Sequence
MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 128 | N-linked (GlcNAc...) asparagine | |||
| 191 |
|
|
||
| 192 | N-linked (GlcNAc...) asparagine | |||
| 350 | N-linked (GlcNAc...) asparagine |
|
G46503DX
G70101JE
G80920RR
G62765YT
G31852PQ
G27058EU
G29184RN
G59626AS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of glycosylphosphatidylinositol (GPI) | Homo sapiens |
Human Protein Atlas