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G1/S-specific cyclin-E2
Summary
- UniProt ID
- O96020
- Gene Symbol
-
- CCNE2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell division
- Cyclin
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| cytosol |
| nucleoplasm |
| centrosome |
| cyclin E1-CDK2 complex |
| cyclin E2-CDK2 complex |
| GO Term |
|---|
| protein kinase binding |
| cyclin-dependent protein serine/threonine kinase regulator activity |
Sequence
MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 35 |
|
|||
| 36 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Association of TriC/CCT with target proteins during biosynthesis | Homo sapiens |
| CDK-mediated phosphorylation and removal of Cdc6 | Homo sapiens |
| Cyclin D associated events in G1 | Homo sapiens |
| Cyclin E associated events during G1/S transition | Homo sapiens |
| DNA Damage/Telomere Stress Induced Senescence | Homo sapiens |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | Homo sapiens |
| G0 and Early G1 | Homo sapiens |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | Homo sapiens |
| SCF(Skp2)-mediated degradation of p27/p21 | Homo sapiens |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | Homo sapiens |
