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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NADH-cytochrome b5 reductase 3
Summary
- UniProt ID
- P00387
- Gene Symbol
-
- CYB5R3
- DIA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative promoter usage
- Alternative splicing
- Cholesterol biosynthesis
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Endoplasmic reticulum
- FAD
- Mitochondrion outer membrane
- Myristate
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nitric oxide biosynthetic process |
| blood circulation |
| cholesterol biosynthetic process |
| GO Term |
|---|
| extracellular region |
| cytoplasm |
| membrane |
| mitochondrion |
| cytosol |
| mitochondrial membrane |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| mitochondrial outer membrane |
| lipid droplet |
| GO Term |
|---|
| NAD binding |
| cytochrome-b5 reductase activity, acting on NAD(P)H |
| AMP binding |
| ADP binding |
| FAD binding |
Sequence
MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 30 |
|
|||
| 31 |
|
|||
| 210 |
|
G49108TO
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neutrophil degranulation | Homo sapiens |
| Phase I - Functionalization of compounds | Homo sapiens |
| Vitamin C (ascorbate) metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1612 | breast cancer | |
| DOID:9854 | lingual-facial-buccal dyskinesia | |
| DOID:162 | cancer | |
| DOID:1781 | thyroid cancer | |
| DOID:1826 | epilepsy | |
| DOID:219 | colon cancer | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2834 | acquired polycythemia | |
| DOID:2838 | stress polycythemia | |
| DOID:2839 | erythropoietin polycythemia |
