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Glycan Structure Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hypoxanthine-guanine phosphoribosyltransferase
Summary
- UniProt ID
- P00492
- Gene Symbol
-
- HPRT1
- HPRT
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P00492
- PubChem
- P00492
- The Human Metabolome Database
- HMDBP00475
- The O-GlcNAc Database
- P00492
- RaftProt
- P00492
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glycosyltransferase
- Gout
- Isopeptide bond
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Purine salvage
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| extracellular exosome |
| cytosol |
Sequence
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Azathioprine ADME | Homo sapiens |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | Homo sapiens |
| Purine salvage | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9521 | Laron syndrome | |
| DOID:9588 | encephalitis | |
| DOID:9719 | neovascular inflammatory vitreoretinopathy | |
| DOID:9744 | type 1 diabetes mellitus | |
| DOID:9854 | lingual-facial-buccal dyskinesia | |
| DOID:9884 | muscular dystrophy | |
| DOID:9923 | developmental coordination disorder | |
| DOID:9952 | acute lymphoblastic leukemia | |
| DOID:9953 | acute biphenotypic leukemia |
