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Repository for lectin-assisted multimodality data
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MIRAGE
Beta-nerve growth factor
Summary
- UniProt ID
- P01138
- Gene Symbol
-
- NGF
- NGFB
- Gene ID
- 4803
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P01138
- PubChem
- P01138
- The Human Metabolome Database
- HMDBP02581
- Re-Glyco
- P01138
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Growth factor
- Lipid-binding
- Metalloprotease inhibitor
- Neurodegeneration
- Neuropathy
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| axon |
| dendrite |
| Golgi lumen |
| cytosol |
| synaptic vesicle |
| endosome lumen |
| GO Term |
|---|
| nerve growth factor receptor binding |
| growth factor activity |
| metalloendopeptidase inhibitor activity |
| lipid binding |
Sequence
MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ARMS-mediated activation | Homo sapiens |
| Axonal growth stimulation | Homo sapiens |
| Ceramide signalling | Homo sapiens |
| Frs2-mediated activation | Homo sapiens |
| NADE modulates death signalling | Homo sapiens |
| NF-kB is activated and signals survival | Homo sapiens |
| NFG and proNGF binds to p75NTR | Homo sapiens |
| NGF processing | Homo sapiens |
| NRAGE signals death through JNK | Homo sapiens |
| NRIF signals cell death from the nucleus | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060001 | withdrawal disorder | |
| DOID:0070145 | hereditary sensory and autonomic neuropathy type 5 | |
| DOID:0070355 | overactive bladder syndrome | |
| DOID:13949 | interstitial cystitis | |
| DOID:2559 | opiate dependence | |
| DOID:2841 | asthma | |
| DOID:2986 | IgA glomerulonephritis | |
| DOID:3312 | bipolar disorder | |
| DOID:5844 | myocardial infarction | |
| DOID:783 | end stage renal disease |
