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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
H-2 class II histocompatibility antigen, E-D alpha chain
Summary
- UniProt ID
- P01904
- Gene Symbol
-
- H2-Ea
- Organism
- Mus musculus (house mouse)
External Links
Annotation
- Keyword
-
- 3D-structure
- Disulfide bond
- Glycoprotein
- MHC II
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| lysosome |
| plasma membrane |
| MHC class II protein complex |
| lysosomal membrane |
| late endosome membrane |
| GO Term |
|---|
| MHC class II protein complex binding |
| peptide antigen binding |
Sequence
MATIGALVLRFFFIAVLMSSQKSWAIKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAKFASFEAQGALANIAVDKANLDVMKERSNNTPDANVAPEVTVLSRSPVNLGEPNILICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHYLTFLPSTDDFYDCEVDHWGLEEPLRKTWEFEEKTLLPETKENVMCALGLFVGLVGIVVGIILIMKGIKKRNVVERRQGAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 143 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream TCR signaling | Mus musculus |
| Generation of second messenger molecules | Mus musculus |
| MHC class II antigen presentation | Mus musculus |
| PD-1 signaling | Mus musculus |
| Phosphorylation of CD3 and TCR zeta chains | Mus musculus |
| Translocation of ZAP-70 to Immunological synapse | Mus musculus |
