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MIRAGE
Band 3 anion transport protein

Summary
UniProt ID
P02730
Gene Symbol
  • AE1
  • DI
  • EPB3
  • SLC4A1
Gene ID
6521
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P02730
PubChem
P02730
The O-GlcNAc Database
P02730
RaftProt
P02730
O-GlcNAcAtlas
P02730
Re-Glyco
P02730
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Anion exchange
  • Blood group antigen
  • Cell membrane
  • Direct protein sequencing
  • Disease variant
  • Elliptocytosis
  • Glycoprotein
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 9 entries
GO Term
plasma membrane
membrane
basolateral plasma membrane
Z disc
cytoplasmic side of plasma membrane
extracellular exosome
blood microparticle
ankyrin-1 complex
cortical cytoskeleton
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMPV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
162
224
642 N-linked (GlcNAc...) (complex) asparagine
745
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Bicarbonate transporters Homo sapiens
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) Homo sapiens
Erythrocytes take up carbon dioxide and release oxygen Homo sapiens
Erythrocytes take up oxygen and release carbon dioxide Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:12971 hereditary spherocytosis
DOID:14219 renal tubular acidosis
DOID:589 congenital hemolytic anemia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025