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Granzyme B(G,H)

Summary

UniProt ID

P04187

Gene Symbol

Ctla-1
Ctla1
Gzmb

Gene ID

14939

Organism

Mus musculus (house mouse)

External Links

PubChem: P04187
Re-Glyco: P04187

Annotation

Keyword

Apoptosis
Cytolysis
Direct protein sequencing
Disulfide bond
Glycoprotein
Lysosome
Reference proteome
Secreted
Serine protease
Signal
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
cytosol
cytolytic granule
extracellular space
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
protein maturation
pyroptosis
granzyme-mediated programmed cell death signaling pathway
proteolysis involved in protein catabolic process
T cell mediated cytotoxicity
natural killer cell mediated cytotoxicity
apoptotic process
killing of cells of another organism
defense response to bacterium

Displaying **all 2** entries
GO Term
serine-type endopeptidase activity
serine-type peptidase activity

Annotation information from UniProt.

Sequence

MKILLLLLTLSLASRTKAGEIIGGHEVKPHSRPYMALLSIKDQQPEAICGGFLIREDFVLTAAHCEGSIINVTLGAHNIKEQEKTQQVIPMVKCIPHPDYNPKTFSNDIMLLKLKSKAKRTRAVRPLNLPRRNVNVKPGDVCYVAGWGRMAPMGKYSNTLQEVELTVQKDRECESYFKNRYNKTNQICAGDPKTKRASFRGDSGGPLVCKKVAAGIVSYGYKDGSPPRAFTKVSSFLSWIKKTMKSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
71	N-linked (GlcNAc...) asparagine			UniProt
182	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Activation of BID and translocation to mitochondria	Mus musculus
Pyroptosis	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements