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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transforming growth factor beta-1 proprotein
Summary
- UniProt ID
- P04202
- Gene Symbol
-
- Tgfb1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003273
- PubChem
- P04202
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of chemokine (C-X-C motif) ligand 2 production |
| GO Term |
|---|
| cell surface |
| blood microparticle |
| extracellular space |
| nucleus |
| cytoplasm |
| microvillus |
| secretory granule |
| axon |
| extracellular matrix |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| protein-containing complex binding |
| protein serine/threonine kinase activator activity |
Sequence
MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYEKTKDISHSIYMFFNTSDIREAVPEPPLLSRAELRLQRLKSSVEQHVELYQKYSNNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 82 | N-linked (GlcNAc...) asparagine |
|
||
| 136 | N-linked (GlcNAc...) asparagine |
|
||
| 176 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Mus musculus |
| Downregulation of TGF-beta receptor signaling | Mus musculus |
| Molecules associated with elastic fibres | Mus musculus |
| Platelet degranulation | Mus musculus |
| RUNX3 regulates CDKN1A transcription | Mus musculus |
| RUNX3 regulates p14-ARF | Mus musculus |
| Regulation of RUNX3 expression and activity | Mus musculus |
| Syndecan interactions | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Mus musculus |
