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H-2 class II histocompatibility antigen gamma chain

Summary

UniProt ID

P04441

Gene Symbol

Cd74
Ii

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003275
GlyGen: P04441
PubChem: P04441
RaftProt: P04441

Annotation

Keyword

Adaptive immunity
Alternative splicing
Cell membrane
Chaperone
Disulfide bond
Endoplasmic reticulum
Endosome
Golgi apparatus
Lysosome
Phosphoprotein
Proteoglycan
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

Displaying entries **41 - 44** of 44 in total

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GO Term
positive regulation of adaptive immune response
positive regulation of type 2 immune response
intracellular protein transport
defense response

Displaying entries **11 - 16** of 16 in total

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GO Term
extracellular region
extracellular space
nucleus
cytoplasm
lysosome
plasma membrane

Displaying **all 8** entries
GO Term
macrophage migration inhibitory factor binding
MHC class II protein binding, via antigen binding groove
amyloid-beta binding
cytokine receptor activity
CD4 receptor binding
protein folding chaperone
nitric-oxide synthase binding
MHC class II protein binding

Annotation information from UniProt.

Sequence

MDDQRDLISNHEQLPILGNRPREPERCSRGALYTGVSVLVALLLAGQATTAYFLYQQQGRLDKLTITSQNLQLESLRMKLPKSAKPVSQMRMATPLLMRPMSMDNMLLGPVKNVTKYGNMTQDHVMHLLTRSGPLEYPQLKGTFPENLKHLKNSMDGVNWKIFESWMKQWLLFEMSKNSLEEKKPTEAPPKVLTKCQEEVSHIPAVYPGAFRPKCDENGNYLPLQCHGSTGYCWCVFPNGTEVPHTKSRGRHNCSEPLDMEDLSSGLGVTRQELGQVTL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
113	N-linked (GlcNAc...) asparagine			UniProt GlyGen
119	N-linked (GlcNAc...) asparagine		G24748EV	GlycoProtDB UniProt GlyGen
239				GlycoProtDB
253			G31852PQ	GlycoProtDB GlyGen
265	O-linked (Xyl...) (chondroitin sulfate) serine	3422739		UniProt GlyGen