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Tropomyosin alpha-1 chain

Summary

UniProt ID

P04692

Gene Symbol

Tpm1
Alpha-tm
Tpma

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P04692
The O-GlcNAc Database: P04692
O-GlcNAcAtlas: P04692

Annotation

Keyword

3D-structure
Acetylation
Actin-binding
Alternative splicing
Coiled coil
Cytoskeleton
Direct protein sequencing
Muscle protein
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

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GO Term
regulation of cell shape
positive regulation of stress fiber assembly
ventricular cardiac muscle tissue morphogenesis
muscle filament sliding
positive regulation of ATP-dependent activity
actin filament organization
sarcomere organization
in utero embryonic development
muscle contraction
negative regulation of cell migration

Displaying **all 8** entries
GO Term
bleb
ruffle membrane
cytoplasm
actin filament
actin cytoskeleton
myofibril
protein-containing complex
stress fiber

Displaying **all 7** entries
GO Term
cytoskeletal protein binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
actin filament binding
disordered domain specific binding
actin binding

Annotation information from UniProt.

Sequence

MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	GlyTouCan ID	Source
87	G49108TO	GlyGen The O-GlcNAc Database
123	G49108TO	GlyGen The O-GlcNAc Database
132	G49108TO	GlyGen The O-GlcNAc Database
186	G49108TO	GlyGen The O-GlcNAc Database
206	G49108TO	GlyGen The O-GlcNAc Database