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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cytochrome b-245 heavy chain
Summary
- UniProt ID
- P04839
- Gene Symbol
-
- CYBB
- NOX2
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P04839
- PubChem
- P04839
- The Human Metabolome Database
- HMDBP01763
- RaftProt
- P04839
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Chronic granulomatous disease
- Direct protein sequencing
- Disease variant
- Electron transport
- FAD
- Glycoprotein
- Heme
- Isopeptide bond
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Voltage-gated channel
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| perinuclear endoplasmic reticulum |
| nuclear envelope |
| plasma membrane |
| dendrite |
| neuronal cell body |
| phagocytic vesicle membrane |
| monoatomic ion channel complex |
| specific granule membrane |
| NADPH oxidase complex |
| GO Term |
|---|
| metal ion binding |
| heme binding |
| protein heterodimerization activity |
| flavin adenine dinucleotide binding |
| superoxide-generating NAD(P)H oxidase activity |
Sequence
MGNWAVNEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCNNATNLKLKKIYFYWLCRDTHAFEWFADLLQLLESQMQERNNAGFLSYNIYLTGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPEALAETLSKQSISNSESGPRGVHFIFNKENF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 122 |
|
|
||
| 132 | N-linked (GlcNAc...) asparagine | |||
| 133 |
|
|
||
| 149 | N-linked (GlcNAc...) asparagine | |||
| 154 |
|
|
||
| 240 | N-linked (GlcNAc...) asparagine | |||
| 429 |
|
|
G80920RR
G62765YT
G51640FO
G90659AW
G84820NF
G15664MX
G83460ZZ
G72747WU
G25079LO
G39446WN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cross-presentation of particulate exogenous antigens (phagosomes) | Homo sapiens |
| Detoxification of Reactive Oxygen Species | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RAC2 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHO GTPases Activate NADPH Oxidases | Homo sapiens |
| ROS and RNS production in phagocytes | Homo sapiens |
| VEGFA-VEGFR2 Pathway | Homo sapiens |
Human Protein Atlas