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Major prion protein

Summary

UniProt ID

P04925

Gene Symbol

Prnp
Prn-p
Prp

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003279

GlyConnect

2499

GlyGen

P04925

PubChem

P04925

The O-GlcNAc Database

P04925

RaftProt

P04925

Annotation

Keyword

3D-structure
Cell membrane
Copper
Direct protein sequencing
Disulfide bond
GPI-anchor
Golgi apparatus
Hydroxylation
Metal-binding
Prion
Reference proteome
Repeat
Signal
Zinc

Gene Ontology (GO)

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GO Term
negative regulation of protein phosphorylation
nucleobase-containing compound metabolic process
protein homooligomerization
cellular response to copper ion
positive regulation of protein targeting to membrane
negative regulation of long-term synaptic potentiation
regulation of potassium ion transmembrane transport
negative regulation of amyloid-beta formation
negative regulation of dendritic spine maintenance
negative regulation of amyloid precursor protein catabolic process

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GO Term
inclusion body
cytosol
membrane raft
endoplasmic reticulum
cell surface
postsynaptic density
side of membrane
Golgi apparatus
plasma membrane
membrane

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GO Term
molecular adaptor activity
protein-folding chaperone binding
aspartic-type endopeptidase inhibitor activity
type 5 metabotropic glutamate receptor binding
identical protein binding
ATP-dependent protein binding
transmembrane transporter binding
molecular function activator activity
amyloid-beta binding
copper ion binding

Annotation information from UniProt.

Sequence

MANLGYWLLALFVTMWTDVGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGTWGQPHGGGWGQPHGGSWGQPHGGSWGQPHGGGWGQGGGTHNQWNKPSKPKTNLKHVAGAAAAGAVVGGLGGYMLGSAMSRPMIHFGNDWEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCVTQYQKESQAYYDGRRSSSTVLFSSPPVILLISFLIFLIVG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
180	N-linked (GlcNAc...) asparagine		G60967DT G39945EK G90443NH G25180HQ G26014MK G76519VT G91623TN G99035PG G32671AN G65219TP G71071YT G26896YH G94373HA G24132CP G82138AT G62837IG G19099PA G52003QG G94163JU G65365UP G26371XR G35687VS G29895JE G07682PQ G45045RU G15791TK G57818FI G92129PT	UniProt GlyGen
196	N-linked (GlcNAc...) asparagine	19349973	G41205CB G43549OX G43953LS G05395FV G29721UX G63046OH G33785ND G74320MK G26014MK G91623TN G94373HA G24132CP G82138AT G62837IG G52003QG G94163JU G40012WS G22137OG G35687VS G65550TC G25495RY G64527OM G05724UK G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
			G49108TO	GlyGen The O-GlcNAc Database