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MIRAGE
Plasminogen activator inhibitor 1

Summary
UniProt ID
P05121
Gene Symbol
  • PAI1
  • PLANH1
  • SERPINE1
Gene ID
5054
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011385
GlyConnect
GlyGen
P05121
PubChem
P05121
The Human Metabolome Database
HMDBP01864
Re-Glyco
P05121
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Glycoprotein
  • Reference proteome
  • Secreted
  • Serine protease inhibitor
  • Signal
Gene Ontology (GO)
Displaying all 8 entries
GO Term
platelet alpha granule lumen
extracellular region
extracellular space
plasma membrane
collagen-containing extracellular matrix
extracellular exosome
serine protease inhibitor complex
peptidase inhibitor complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
232
288
352 N-linked (GlcNAc...) asparagine
359
360
362
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
BMAL1:CLOCK,NPAS2 activates circadian gene expression Homo sapiens
Dissolution of Fibrin Clot Homo sapiens
ECM proteoglycans Homo sapiens
Platelet degranulation Homo sapiens
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Homo sapiens
Disease
Displaying entries 1 - 10 of 26 in total
DO ID Disease Name Source
DOID:0060181 ischemic colitis
DOID:0060903 thrombosis
DOID:10247 pleurisy
DOID:11054 urinary bladder cancer
DOID:11695 portal vein thrombosis
DOID:11713 diabetic angiopathy
DOID:12361 Graves' disease
DOID:13025 retinopathy of prematurity
DOID:13207 proliferative diabetic retinopathy
DOID:14018 alcoholic liver cirrhosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025