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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Propionyl-CoA carboxylase beta chain, mitochondrial
Summary
- UniProt ID
- P05166
- Gene Symbol
-
- PCCB
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P05166
- PubChem
- P05166
- The Human Metabolome Database
- HMDBP00258
- The O-GlcNAc Database
- P05166
- O-GlcNAcAtlas
- P05166
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Ligase
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Transit peptide
- Gene Ontology (GO)
| GO Term |
|---|
| short-chain fatty acid catabolic process |
| branched-chain amino acid metabolic process |
| fatty acid metabolic process |
| GO Term |
|---|
| catalytic complex |
| mitochondrion |
| mitochondrial matrix |
| cytosol |
| GO Term |
|---|
| ATP binding |
| propionyl-CoA carboxylase activity |
Sequence
MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVEAAQAEYIEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 45 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Biotin transport and metabolism | Homo sapiens |
| Defective HLCS causes multiple carboxylase deficiency | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
| Propionyl-CoA catabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1227 | neutropenia | |
| DOID:12450 | pancytopenia | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:12932 | endomyocardial fibrosis | |
| DOID:12987 | agranulocytosis | |
| DOID:13884 | sick sinus syndrome | |
| DOID:14320 | generalized anxiety disorder | |
| DOID:1443 | cerebral degeneration | |
| DOID:14701 | propionic acidemia | |
| DOID:1588 | thrombocytopenia |
