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Hexokinase-1
Summary
- UniProt ID
- P05708
- Gene Symbol
-
- Hk1
- Gene ID
- 25058
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Allosteric enzyme
- Cytoplasm
- Direct protein sequencing
- Glycolysis
- Inflammatory response
- Innate immunity
- Kinase
- Mitochondrion outer membrane
- Phosphoprotein
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| protein-containing complex |
| cytosol |
| mitochondrial outer membrane |
| caveola |
| membrane raft |
| GO Term |
|---|
| ATP binding |
| ATP hydrolysis activity |
| identical protein binding |
| protein-containing complex binding |
| glucokinase activity |
| hexokinase activity |
| glucose binding |
| fructokinase activity |
| peptidoglycan binding |
| mannokinase activity |
Sequence
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDKEGIQNAKEILTRLGVEPSDVDCVSVQHICTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNVEMVEGNQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSEDGSGKGAALITAVGVRLRGDPSIA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 259 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycolysis | Rattus norvegicus |
| Synthesis of GDP-mannose | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11054 | urinary bladder cancer | |
| DOID:9970 | obesity |
