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T-cell surface glycoprotein CD4

Summary

UniProt ID

P06332

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

PubChem: P06332

Annotation

Keyword

Adaptive immunity
Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Palmitate
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 23 in total

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GO Term
positive regulation of DNA-templated transcription
defense response to Gram-negative bacterium
adaptive immune response
cell adhesion
cell surface receptor signaling pathway
T cell differentiation
macrophage differentiation
positive regulation of T cell proliferation
T cell activation
T cell selection

Displaying **all 6** entries
GO Term
plasma membrane
membrane raft
endoplasmic reticulum lumen
endoplasmic reticulum membrane
external side of plasma membrane
cell surface

Displaying entries **1 - 10** of 11 in total

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GO Term
signaling receptor binding
zinc ion binding
MHC class II protein complex binding
interleukin-16 binding
interleukin-16 receptor activity
coreceptor activity
immunoglobulin binding
protein kinase binding
protein homodimerization activity
protein tyrosine kinase binding

Annotation information from UniProt.

Sequence

MCRAISLRRLLLLLLQLSQLLAVTQGKTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTVFLACVLGGSFGFLGFLGLCILCCVRCRHQQRQAARMSQIKRLLSEKKTCQCPHRMQKSHNLI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
187	N-linked (GlcNAc...) asparagine	UniProt
298	N-linked (GlcNAc...) asparagine	UniProt
323	N-linked (GlcNAc...) asparagine	UniProt
392	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Alpha-defensins	Mus musculus
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
Downstream TCR signaling	Mus musculus
Generation of second messenger molecules	Mus musculus
Other interleukin signaling	Mus musculus
PD-1 signaling	Mus musculus
Phosphorylation of CD3 and TCR zeta chains	Mus musculus
Translocation of ZAP-70 to Immunological synapse	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements