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Sodium/potassium-transporting ATPase subunit alpha-1

Summary

UniProt ID

P06685

Gene Symbol

Atp1a1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P06685
PubChem: P06685
The O-GlcNAc Database: P06685
RaftProt: P06685

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cell membrane
Cell projection
Direct protein sequencing
Magnesium
Metal-binding
Phosphoprotein
Reference proteome
Sodium/potassium transport
Translocase
Transmembrane helix

Gene Ontology (GO)

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GO Term
regulation of sodium ion transport
sodium ion transport
intracellular sodium ion homeostasis
regulation of blood pressure
sodium ion homeostasis
transmembrane transport
heart contraction
negative regulation of glucocorticoid biosynthetic process
negative regulation of heart contraction
positive regulation of heart contraction

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GO Term
caveola
endosome
endoplasmic reticulum
sperm flagellum
sodium:potassium-exchanging ATPase complex
postsynaptic density
membrane
axon
protein-containing complex
melanosome

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GO Term
phosphatase activity
ATP hydrolysis activity
ADP binding
P-type sodium:potassium-exchanging transporter activity
ATP binding
P-type potassium transmembrane transporter activity
phosphatidylinositol 3-kinase binding
protein kinase binding
sodium ion binding
steroid hormone binding

Annotation information from UniProt.

Sequence

MGKGVGRDKYEPAAVSEHGDKKSKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTPARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIRSATEEEPPNDDLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEDVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVMEMREKYTKIVEIPFNSTNKYQLSIHKNPNASEPKHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDEVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites