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Carcinoembryonic antigen-related cell adhesion molecule 5
Summary
- UniProt ID
- P06731
- Gene Symbol
-
- CEACAM5
- CEA
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0015590
- GlyConnect
- GlyGen
- P06731
- PubChem
- P06731
- RaftProt
- P06731
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Cell adhesion
- Cell membrane
- Disulfide bond
- GPI-anchor
- Immunoglobulin domain
- Oncogene
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| basolateral plasma membrane |
| apical plasma membrane |
| cell surface |
| side of membrane |
| extracellular region |
| plasma membrane |
| membrane |
| GO Term |
|---|
| protein tyrosine kinase binding |
| identical protein binding |
| protein homodimerization activity |
| GPI anchor binding |
Sequence
MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 288 | N-linked (GlcNAc...) asparagine | |||
| 292 | N-linked (GlcNAc...) asparagine |
|
||
| 309 | N-linked (GlcNAc...) asparagine |
|
||
| 330 | N-linked (GlcNAc...) asparagine |
|
||
| 351 | N-linked (GlcNAc...) asparagine | |||
| 360 | N-linked (GlcNAc...) asparagine | |||
| 375 | N-linked (GlcNAc...) asparagine | |||
| 432 | N-linked (GlcNAc...) asparagine | |||
| 466 | N-linked (GlcNAc...) asparagine |
|
||
| 480 | N-linked (GlcNAc...) asparagine |
|
G42459UQ
G67506FN
G25541YH
G45883VE
G90093AU
G06110VR
G38663NM
G88976TU
G64130AC
G70375MX
G70822IO
G91636VS
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111344 | myeloproliferative disorder with eosinophilia | |
| DOID:10155 | intestinal cancer | |
| DOID:1024 | leprosy | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10354 | breast fibrocystic disease |
