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Receptor-type tyrosine-protein phosphatase C

Summary

UniProt ID

P06800

Gene Symbol

Ly-5
Ptprc

Gene ID

19264

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003294

GlyConnect

Receptor-type tyrosine-protein phosphatase C

PubChem

P06800

RaftProt

P06800

Re-Glyco

P06800

Annotation

Keyword

Alternative splicing
Cell membrane
Direct protein sequencing
Glycoprotein
Phosphoprotein
Protein phosphatase
Reference proteome
Repeat
Signal
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
cell periphery
external side of plasma membrane
cell surface
focal adhesion
cytoplasmic side of plasma membrane
membrane raft
membrane microdomain
bleb
plasma membrane
synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of cytokine-mediated signaling pathway
regulation of cell cycle
negative regulation of T cell mediated cytotoxicity
regulation of humoral immune response mediated by circulating immunoglobulin
negative regulation of protein kinase activity
negative regulation of cell adhesion involved in substrate-bound cell migration
regulation of interleukin-8 production
plasma membrane raft distribution
negative thymic T cell selection
negative regulation of receptor signaling pathway via JAK-STAT

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GO Term
signaling receptor binding
heparin binding
non-membrane spanning protein tyrosine phosphatase activity
protein tyrosine phosphatase activity
protein kinase binding
ankyrin binding
spectrin binding
heparan sulfate proteoglycan binding
transmembrane receptor protein tyrosine phosphatase activity
histone H2AXY142 phosphatase activity

Annotation information from UniProt.

Sequence

MTMGLWLKLLAFGFALLDTEVFVTGQTPTPSDELSTTENALLLPQSDPLPARTTESTPPSISERGNGSSETTYHPGVLSTLLPHLSPQPDSQTPSAGGADTQTFSSQADNPTLTPAPGGGTDPPGVPGERTVPGTIPADTAFPVDTPSLARNSSAASPTHTSNVSTTDISSGASLTTLTPSTLGLASTDPPSTTIATTTKQTCAAMFGNITVNYTYESSNQTFKADLKDVQNAKCGNEDCENVLNNLEECSQIKNISVSNDSCAPATTIDLYVPPGTDKFSLHDCTPKEKANTSICLEWKTKNLDFRKCNSDNISYVLHCEPENNTKCIRRNTFIPERCQLDNLRAQTNYTCVAEILYRGVKLVKNVINVQTDLGIPETPKPSCGDPAARKTLVSWPEPVSKPESASKPHGYVLCYKNNSEKCKSLPNNVTSFEVESLKPYKYYEVSLLAYVNGKIQRNGTAEKCNFHTKADRPDKVNGMKTSRPTDNSINVTCGPPYETNGPKTFYILVVRSGGSFVTKYNKTNCQFYVDNLYYSTDYEFLVSFHNGVYEGDSVIRNESTNFNAKALIIFLVFLIIVTSIALLVVLYKIYDLRKKRSSNLDEQQELVERDDEKQLMDVEPIHSDILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKDARKPHNQNKNRYVDILPYDYNRVELSEINGDAGSTYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFKDIVVTINDHKRCPDYIIQKLNVAHKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAEGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHSCLHNMKKRDPPSDPSPLEAEYQRLPSYRSWRTQHIGNQEENKKKNRNSNVVPYDFNRVPLKHELEMSKESEPESDESSDDDSDSEETSKYINASFVMSYWKPEMMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELVNGDQEVCAQYWGEGKQTYGDMEVEMKDTNRASAYTLRTFELRHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVSMIQDLKQKLPKASPEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETEDVVDVFQVVKSLRKARPGVVCSYEQYQFLYDIIASIYPAQNGQVKKTNSQDKIEFHNEVDGGKQDANCVRPDGPLNKAQEDSRGVGTPEPTNSAEEPEHAANGSASPAPTQSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	Source
66	N-linked (GlcNAc...) asparagine	UniProt
152	N-linked (GlcNAc...) asparagine	UniProt
163	N-linked (GlcNAc...) asparagine	UniProt
209	N-linked (GlcNAc...) asparagine	UniProt
213	N-linked (GlcNAc...) asparagine	UniProt
220	N-linked (GlcNAc...) asparagine	UniProt
253		GlycoProtDB
255	N-linked (GlcNAc...) asparagine	UniProt
258		GlycoProtDB
260	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Neutrophil degranulation	Mus musculus
Other semaphorin interactions	Mus musculus
Phosphorylation of CD3 and TCR zeta chains	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements