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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Lipoprotein lipase
Summary
- UniProt ID
- P06858
- Gene Symbol
-
- LPL
- LIPD
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P06858
- PubChem
- P06858
- SwissLipids
- The Human Metabolome Database
- HMDBP00310
- The O-GlcNAc Database
- P06858
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Chylomicron
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Hydrolase
- Hyperlipidemia
- Lipid degradation
- Metal-binding
- Nitration
- Reference proteome
- Signal
- VLDL
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| catalytic complex |
| extracellular region |
| extracellular space |
| cell surface |
| very-low-density lipoprotein particle |
| chylomicron |
| GO Term |
|---|
| lipoprotein lipase activity |
| phospholipase activity |
| triglyceride lipase activity |
| phospholipase A1 activity |
Sequence
MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 70 | N-linked (GlcNAc...) asparagine | |||
| 386 | N-linked (GlcNAc...) asparagine |
|
||
| 417 |
|
|
||
|
|
G50427EO
G77582RK
G20312EM
G11629QQ
G86795LJ
G96577RX
G81263BG
G47012YE
G51413EV
G08146BT
G22310AV
G66163OV
G71146HJ
G75983OB
G42358LZ
G48414YA
G72797UR
G25451PN
G45495MK
G84452RH
G06356OH
G37868ZX
G80920RR
G23863VK
G57818FI
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly of active LPL and LIPC lipase complexes | Homo sapiens |
| Chylomicron remodeling | Homo sapiens |
| Retinoid metabolism and transport | Homo sapiens |
| Transcriptional regulation of white adipocyte differentiation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050782 | Zollinger-Ellison syndrome | |
| DOID:0050830 | peripheral artery disease | |
| DOID:0050873 | follicular lymphoma | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060357 | chylomicron retention disease | |
| DOID:0060870 | isolated growth hormone deficiency | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:0070202 | familial partial lipodystrophy type 2 | |
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease |
