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Transforming growth factor beta-1 proprotein
Summary
- UniProt ID
- P07200
- Gene Symbol
-
- TGFB1
- Organism
- Sus scrofa (pig)
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of protein secretion |
| regulation of binding |
| regulation of DNA binding |
| positive regulation of protein metabolic process |
| positive regulation of cell division |
| GO Term |
|---|
| extracellular space |
| nucleus |
| cytoplasm |
| extracellular matrix |
| cell surface |
| blood microparticle |
Sequence
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESVEPEPEPEADYYAKEVTRVLMVESGNQIYDKFKGTPHSLYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLTRREAIEGFRLSAHCSCDSKDNTLHVEINGFNSGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Sus scrofa |
| Downregulation of TGF-beta receptor signaling | Sus scrofa |
| Molecules associated with elastic fibres | Sus scrofa |
| Platelet degranulation | Sus scrofa |
| RUNX3 regulates CDKN1A transcription | Sus scrofa |
| RUNX3 regulates p14-ARF | Sus scrofa |
| Regulation of RUNX3 expression and activity | Sus scrofa |
| Syndecan interactions | Sus scrofa |
| TGF-beta receptor signaling activates SMADs | Sus scrofa |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Sus scrofa |
