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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Insulin-like growth factor II
Summary
- UniProt ID
- P07456
- Gene Symbol
-
- IGF2
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- Glucose metabolism
- Glycoprotein
- Growth factor
- Hormone
- Mitogen
- Osteogenesis
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| insulin-like growth factor receptor binding |
| integrin binding |
| hormone activity |
| growth factor activity |
| protein serine/threonine kinase activator activity |
Sequence
MGITAGKSVLVLLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASTTVLPDDVTAYPVGKFFQYDIWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSHRPLIALPTQDPATHGGASSKASSD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 106 | O-linked (GalNAc...) threonine |
|
||
| 154 | O-linked (GalNAc...) serine | |||
| 163 | O-linked (GalNAc...) threonine |
G29931IJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| IRS-related events triggered by IGF1R | Bos taurus |
| Platelet degranulation | Bos taurus |
| Regulation of IGF Activity by IGFBP | Bos taurus |
| SHC-related events triggered by IGF1R | Bos taurus |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | Bos taurus |
