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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Bisphosphoglycerate mutase
Summary
- UniProt ID
- P07738
- Gene Symbol
-
- BPGM
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P07738
- The Human Metabolome Database
- HMDBP00266
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Congenital erythrocytosis
- Direct protein sequencing
- Disease variant
- Glycation
- Glycolysis
- Hereditary hemolytic anemia
- Hydrolase
- Isomerase
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| cytosol |
| GO Term |
|---|
| bisphosphoglycerate mutase activity |
| hydrolase activity |
| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
Sequence
MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 3 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 5 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 18 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 43 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 159 | N-linked (Glc) (glycation) lysine |
|
||
| 197 | N-linked (Glc) (glycation) lysine; in vitro |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycolysis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060474 | familial erythrocytosis 2 | |
| DOID:10211 | cholelithiasis | |
| DOID:11151 | cholecystolithiasis | |
| DOID:11755 | choledocholithiasis | |
| DOID:1949 | cholecystitis | |
| DOID:2834 | acquired polycythemia | |
| DOID:2838 | stress polycythemia | |
| DOID:2839 | erythropoietin polycythemia | |
| DOID:720 | normocytic anemia | |
| DOID:8432 | polycythemia |
