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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Monocyte differentiation antigen CD14
Summary
- UniProt ID
- P08571
- Gene Symbol
-
- CD14
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P08571
- PubChem
- P08571
- The Human Metabolome Database
- HMDBP13758
- RaftProt
- P08571
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
Sequence
MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 37 | N-linked (GlcNAc...) asparagine |
|
||
| 151 | N-linked (GlcNAc...) asparagine |
|
||
| 282 | N-linked (GlcNAc...) asparagine | |||
| 323 | N-linked (GlcNAc...) asparagine |
|
||
| 336 | O-linked (GalNAc...) threonine | |||
| 362 |
|
|||
| 364 |
|
|||
|
|
|
G20312EM
G40926MX
G00912UN
G42358LZ
G48414YA
G45495MK
G84452RH
G42962KI
G44215PV
G06356OH
G37868ZX
G59626AS
G23294PN
G80920RR
G23863VK
G57818FI
G84820NF
G37399XV
G82463GQ
G62765YT
G10486CT
G22140GZ
G50045TK
G72735IY
G72291OX
G95865ZB
G05724UK
G31852PQ
G82020ZR
G33609NS
G39188ZX
G80966KZ
G57776ZU
G06110VR
G55220VL
G02402FF
G66538GV
G30221QT
G20706XG
G60177UT
G15664MX
G46503DX
G70101JE
G64527OM
G66676MI
G41247ZX
G02815KT
G27391WQ
G29931IJ
G43417UB
G29068FM
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| IKK complex recruitment mediated by RIP1 | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Homo sapiens |
| IRAK4 deficiency (TLR2/4) | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| MyD88 deficiency (TLR2/4) | Homo sapiens |
| MyD88-independent TLR4 cascade | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070042 | Coffin-Siris syndrome 1 | |
| DOID:0070324 | systemic Epstein-Barr virus positive T-cell lymphoma of childhood | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:0080188 | chronic myelomonocytic leukemia | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080334 | aortic valve disease 2 | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0090016 | chromosome 5q deletion syndrome | |
| DOID:0090018 | autosomal dominant familial periodic fever |
