Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement C5
Summary
- UniProt ID
- P08650
- Gene Symbol
-
- C5
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P08650
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Complement alternate pathway
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Membrane attack complex
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| membrane attack complex |
| GO Term |
|---|
| C5a anaphylatoxin chemotactic receptor binding |
| endopeptidase inhibitor activity |
Sequence
MGLWGLLCLLIFLDKTWGQEQTYVISAPKIFRVGSSENVVIQAHGYTEAFDATISLKSYPDKKVTYSSGYVNLSPENKFQNSALLTLPPKQFPRDENPVSHVYLEVVSMHFSKSKKIPITYDNGFLFIHTDKPVYTPDQSVKIRVYSLSDDLKPAKRETVLTFVDPEGTEVDIVEENDYTGIISFPDFKIPSNPKYGVWTIKAKYKKDFTTTGTAYFEVKEYVLPRFSVSIEPESNFIGYKNFKNFEITVKARYFYNKMVPDAEVYIFFGLREDIKEDEKQMMHKAMQAATLMDGAAQTCWLAETEVREINYNMFEDRNNNYSYIACTVTESSGGFSEEAEIPGIKYVLSPYTLNLVATPLFLKPGIPFSIKVQVKDSLEQLVGGVPVTLMAQTVNVNQETSDLEPKRSITHSADGVASFVVNLPSEVTSLKFEVKTDAPELPEENQASKEYEAVTYSSLSQSYIYIGWTENYKPMLVGEYLNIIVTPKSPYIDKITHYNYLILSKGKIVQYGTKEKLLYSSYQNINIPVTQDMVPSARLLVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDKDVYSPGQTVSLDMVTEADSWVALSAVDSAVYGVRGKAKRAMQRVFQAFDDKSDLGCGAGGGRDNVDVFHLAGLTFLTNANADDSQYHDDSCKEILRPKRDLQLLHQKVEEQAAKYKHRVPKKCCYDGARENKYETCEQRVARVTIGPHCIRAFNECCTIADKIRKESHHKGMLLGRIQIKALLPVMKAEIRSYFPESWLWEVHRVPKRNQLQVALPDSLTTWEIQGIGISDNGICVADTLKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGTMFCVKMSAVEGICTPGSSAASPQTSRSSRCVRQRIEGSSSHLVTFSLLPLEIGLHSINFSLETSFGKEILVKTLRVVPEGIKRESYAGVTLDPRGVYGIVNRRKEFPYRIPLDLVPKTNVKRILSVKGLLIGEFLSTVLSKEGIDILTHLPKGSAEAELMSIVPVFYVFHYLEAGNHWNIFHPDTLARKQSLQKKIKEGLVSVMSYRNADYSYSMWKGASSSAWLTAFALRVLGQVNKYVKQDQYSICNSLLWLIEKCQLENGSFKENSQYLPIKLQGTLPAEAQENTLYLTAFSVIGIRKAIGICPTEKIYTALAKADSFLLERTLPSKSTFTLAIVAYALSLGDRTHPKFRSIVSALKREALVKGDPPIYRFWRDTLQRPDSSAPNSGTAGMVETTAYALLTSLNLKETSYVNPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLHLDMDINVSYKHKGDFYQYKVTEKNFLGRPVEVPLNDDLIVTTGYSSGLATVYVKTVVHKTSVAEEFCSFYLKIDTQEVEASSYLSYSDSGHKRIIACASYKPSKEESASGSSHAVMDILLPTGIGANQEDLRALVEGVDQLLTDYQIKDSHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVYEYHRPDKQCTMIYSTSDTNLQRVCEGAACKCVEADCGQLQAELDLAISADTRKETACKPEIAYAYKVRITSATEENIFVKYTATLLDIYKTGEAAAEKDSEITFIKKISCTNANLVKGKQYLIMGKEALQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVANLDEFAEDIFLNGCE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 72 | N-linked (GlcNAc...) asparagine |
|
||
| 321 | N-linked (GlcNAc...) asparagine |
|
||
| 915 | N-linked (GlcNAc...) asparagine |
|
||
| 1119 | N-linked (GlcNAc...) asparagine |
|
||
| 1318 | N-linked (GlcNAc...) asparagine |
|
||
| 1634 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of C3 and C5 | Rattus norvegicus |
| G alpha (i) signalling events | Rattus norvegicus |
| Peptide ligand-binding receptors | Rattus norvegicus |
| Regulation of Complement cascade | Rattus norvegicus |
| Terminal pathway of complement | Rattus norvegicus |
