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Standards Ontologies Notations
Coagulation factor VII

Summary
UniProt ID
P08709
Gene Symbol
  • F7
Organism
Homo sapiens (human)
External Links
GlyConnect
GlyGen
P08709
PubChem
P08709
The Human Metabolome Database
HMDBP02013
RaftProt
P08709
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Blood coagulation
  • Calcium
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • EGF-like domain
  • Gamma-carboxyglutamic acid
  • Glycoprotein
  • Hydroxylation
  • Pharmaceutical
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
112 O-linked (Glc...) serine; alternate
120 O-linked (Fuc) serine
205 N-linked (GlcNAc...) asparagine
382 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
BMAL1:CLOCK,NPAS2 activates circadian gene expression Homo sapiens
Extrinsic Pathway of Fibrin Clot Formation Homo sapiens
Gamma-carboxylation of protein precursors Homo sapiens
Removal of aminoterminal propeptides from gamma-carboxylated proteins Homo sapiens
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Homo sapiens
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024