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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Protein toll
Summary
- UniProt ID
- P08953
- Gene Symbol
-
- Tl
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Cell membrane
- Cytoplasm
- Developmental protein
- Disulfide bond
- Glycoprotein
- Innate immunity
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| early endosome |
| external side of plasma membrane |
| cell surface |
| cleavage furrow |
| plasma membrane |
Sequence
MSRLKAASELALLVIILQLLQWPGSEASFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMRRCMLPGHTPIASILDYLGIVSPTTLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKNMQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVKLSGNPWMCDCTAKPLLLFTQDNFERIGDRNEMMCVNAEMPTRMVELSTNDICPAEKGVFIALAVVIALTGLLAGFTAALYYKFQTEIKIWLYAHNLLLWFVTEEDLDKDKKFDAFISYSHKDQSFIEDYLVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIVLSQNFIKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYLKMNTYLKWGDPWFWDKLRFALPHRRPVGNIGNGALIKTALKGSTDDKLELIKPSPVTPPLTTPPAEATKNPLVAQLNGVTPHQAIMIANGKNGLTNLYTPNGKSHGNGHINGAFIINTNAKQSDV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 80 | N-linked (GlcNAc...) asparagine |
|
||
| 140 | N-linked (GlcNAc...) asparagine |
|
||
| 175 | N-linked (GlcNAc...) asparagine |
|
||
| 235 | N-linked (GlcNAc...) asparagine |
|
||
| 270 | N-linked (GlcNAc...) asparagine |
|
||
| 275 | N-linked (GlcNAc...) asparagine |
|
||
| 346 | N-linked (GlcNAc...) asparagine |
|
||
| 391 | N-linked (GlcNAc...) asparagine |
|
||
| 482 | N-linked (GlcNAc...) asparagine |
|
||
| 508 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' | Drosophila melanogaster |
| Adaptor protein complex binds to TL receptor at the plasma membrane | Drosophila melanogaster |
| DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' | Drosophila melanogaster |
| DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' | Drosophila melanogaster |
| Formation of the trans-membrane 'signalling complex' | Drosophila melanogaster |
| Neutrophil degranulation | Drosophila melanogaster |
| PLL kinase binds to TUB in the TL receptor 'signalling complex' | Drosophila melanogaster |
| Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' | Drosophila melanogaster |
| Toll Like Receptor 10 (TLR10) Cascade | Drosophila melanogaster |
