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Angiotensin-converting enzyme

Summary

UniProt ID

P09470

Gene Symbol

Ace
Dcp1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003321

GlyConnect

2129

GlyGen

P09470

PubChem

P09470

The O-GlcNAc Database

P09470

RaftProt

P09470

Annotation

Keyword

Alternative promoter usage
Calmodulin-binding
Carboxypeptidase
Cell membrane
Cytoplasm
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

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GO Term
cellular response to glucose stimulus
regulation of hematopoietic stem cell proliferation
cellular response to aldosterone
arachidonic acid secretion
kidney development
neutrophil mediated immunity
regulation of systemic arterial blood pressure by renin-angiotensin
peptide metabolic process
spermatogenesis
female pregnancy

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GO Term
extracellular space
cytoplasm
lysosome
plasma membrane
vesicle
extracellular exosome
brush border membrane
endosome
external side of plasma membrane
basal plasma membrane

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GO Term
chloride ion binding
mitogen-activated protein kinase kinase binding
bradykinin receptor binding
tripeptidyl-peptidase activity
carboxypeptidase activity
metalloendopeptidase activity
metallopeptidase activity
calmodulin binding
peptidyl-dipeptidase activity
zinc ion binding

Annotation information from UniProt.

Sequence

MGAASGQRGRWPLSPPLLMLSLLVLLLQPSPAPALDPGLQPGNFSPDEAGAQLFAESYNSSAEVVMFQSTVASWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDSKLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGWPENQWRPPLPDNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGWPEYNWAPNTARAEGSTAESNRVNFLGLYLEPQQARVGQWVLLFLGVALLVATVGLAHRLYNIRNHHSLRRPHRGPQFGSEVELRHS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
59	N-linked (GlcNAc...) asparagine			UniProt GlyGen
79	N-linked (GlcNAc...) asparagine			UniProt GlyGen
116	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
151	N-linked (GlcNAc...) asparagine	16944957	G25079LO	GlycoProtDB UniProt GlyGen
165	N-linked (GlcNAc...) asparagine		G72735IY G57776ZU	GlycoProtDB UniProt GlyGen GlyConnect
323	N-linked (GlcNAc...) asparagine		G87389XI	GlycoProtDB UniProt GlyGen
514	N-linked (GlcNAc...) asparagine		G64527OM G72735IY G18647XP G82119TF G05724UK G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
528			G72735IY	GlyGen GlyConnect
682	N-linked (GlcNAc...) asparagine			UniProt GlyGen
700	N-linked (GlcNAc...) (complex) asparagine		G23863VK G25637MV G50282JC G74724QE	GlycoProtDB UniProt GlyGen GlyConnect