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Tyrosine-protein kinase Fgr

Summary

UniProt ID

P09769

Gene Symbol

FGR
SRC2

Organism

Homo sapiens (human)

External Links

GlyGen: P09769
PubChem: P09769
The Human Metabolome Database: HMDBP01391
The O-GlcNAc Database: P09769
RaftProt: P09769

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Cell projection
Cytoskeleton
Innate immunity
Mitochondrion inner membrane
Myristate
Palmitate
Phosphoprotein
Proto-oncogene
Reference proteome
SH2 domain
SH3 domain
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 24 in total

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GO Term
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
innate immune response
regulation of innate immune response
regulation of protein kinase activity
bone mineralization
negative regulation of natural killer cell activation
positive regulation of mast cell degranulation
skeletal system morphogenesis

Displaying entries **1 - 10** of 11 in total

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GO Term
actin cytoskeleton
extracellular exosome
aggresome
secretory granule lumen
mitochondrial inner membrane
cytosol
extracellular region
plasma membrane
mitochondrial intermembrane space
extrinsic component of cytoplasmic side of plasma membrane

Displaying **all 8** entries
GO Term
protein tyrosine kinase activity
signaling receptor binding
protein kinase binding
phosphotyrosine residue binding
non-membrane spanning protein tyrosine kinase activity
ATP binding
immunoglobulin receptor binding
Fc-gamma receptor I complex binding

Annotation information from UniProt.

Sequence

MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
181			G49108TO	GlyGen The O-GlcNAc Database
183			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FCGR activation	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
FCGR3A-mediated phagocytosis	Homo sapiens
Neutrophil degranulation	Homo sapiens
Platelet sensitization by LDL	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements