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Tyrosine-protein kinase Fgr

Summary

UniProt ID

P09769

Gene Symbol

FGR
SRC2

Gene ID

2268

Organism

Homo sapiens (human)

External Links

PubChem: P09769
The Human Metabolome Database: HMDBP01391
The O-GlcNAc Database: P09769
RaftProt: P09769
Re-Glyco: P09769

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Cell projection
Cytoskeleton
Innate immunity
Mitochondrion inner membrane
Myristate
Palmitate
Phosphoprotein
Proto-oncogene
Reference proteome
SH2 domain
SH3 domain
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
extracellular region
mitochondrial inner membrane
plasma membrane
actin cytoskeleton
cytosol
mitochondrial intermembrane space
aggresome
ruffle membrane
extracellular exosome
secretory granule lumen

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 24 in total

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GO Term
defense response to Gram-positive bacterium
negative regulation of inflammatory response to antigenic stimulus
regulation of protein kinase activity
myoblast proliferation
immune response-regulating cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
protein autophosphorylation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

Displaying **all 8** entries
GO Term
signaling receptor binding
phosphotyrosine residue binding
Fc-gamma receptor I complex binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding
protein kinase binding
immunoglobulin receptor binding

Annotation information from UniProt.

Sequence

MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
181			G49108TO	The O-GlcNAc Database
183			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FCGR activation	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
FCGR3A-mediated phagocytosis	Homo sapiens
Neutrophil degranulation	Homo sapiens
Platelet sensitization by LDL	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements