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Heat shock 70 kDa protein 1A

Summary

UniProt ID

P0DMW0

Gene Symbol

Hspa1a
Hsp70-1
Hspa1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P0DMW0

Annotation

Keyword

ATP-binding
Acetylation
Chaperone
Cytoskeleton
Methylation
Nucleus
Phosphoprotein
Reference proteome
Secreted
Stress response

Gene Ontology (GO)

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GO Term
regulation of protein ubiquitination
negative regulation of cell growth
negative regulation of apoptotic process
positive regulation of erythrocyte differentiation
ATP metabolic process
chaperone-mediated protein complex assembly
cellular heat acclimation
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of transcription by RNA polymerase II

Displaying entries **1 - 10** of 19 in total

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GO Term
protein-containing complex
cell body
centrosome
membrane raft
aggresome
centriole
COP9 signalosome
nuclear speck
ribonucleoprotein complex
zona pellucida receptor complex

Displaying entries **1 - 10** of 22 in total

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GO Term
denatured protein binding
death receptor agonist activity
transcription regulator inhibitor activity
ATP-dependent protein disaggregase activity
G protein-coupled receptor binding
protease binding
transcription corepressor activity
ATP binding
ATP hydrolysis activity
enzyme binding

Annotation information from UniProt.

Sequence

MAKKTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVNYKGENRSFYPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRERVAAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDSNTLAEKEEFVHKREELERVCNPIISGLYQGAGAPGAGGFGAQAPKGGSGSGPTIEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
636				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
AUF1 (hnRNP D0) binds and destabilizes mRNA	Rattus norvegicus
Attenuation phase	Rattus norvegicus
HSF1-dependent transactivation	Rattus norvegicus
HSP90 chaperone cycle for SHRs	Rattus norvegicus
Mitochondrial unfolded protein response (UPRmt)	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
PKR-mediated signaling	Rattus norvegicus
Regulation of HSF1-mediated heat shock response	Rattus norvegicus