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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Heat shock 70 kDa protein 1A
Summary
- UniProt ID
- P0DMW0
- Gene Symbol
-
- Hspa1a
- Hsp70-1
- Hspa1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- GlyGen
- P0DMW0
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Chaperone
- Cytoskeleton
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Secreted
- Stress response
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| basolateral plasma membrane |
| apical plasma membrane |
| perinuclear region of cytoplasm |
| extracellular space |
| nucleus |
| cytoplasm |
| mitochondrion |
| inclusion body |
| GO Term |
|---|
| protease binding |
| transcription corepressor activity |
| ATP binding |
| ATP hydrolysis activity |
| enzyme binding |
| ubiquitin protein ligase binding |
| histone deacetylase binding |
| protein folding chaperone |
| receptor ligand activity |
| misfolded protein binding |
Sequence
MAKKTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVNYKGENRSFYPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRERVAAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDSNTLAEKEEFVHKREELERVCNPIISGLYQGAGAPGAGGFGAQAPKGGSGSGPTIEEVD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 636 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AUF1 (hnRNP D0) binds and destabilizes mRNA | Rattus norvegicus |
| Attenuation phase | Rattus norvegicus |
| HSF1-dependent transactivation | Rattus norvegicus |
| HSP90 chaperone cycle for SHRs | Rattus norvegicus |
| Mitochondrial unfolded protein response (UPRmt) | Rattus norvegicus |
| Neutrophil degranulation | Rattus norvegicus |
| PKR-mediated signaling | Rattus norvegicus |
| Regulation of HSF1-mediated heat shock response | Rattus norvegicus |
