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MIRAGE
ORF3a protein
Summary
- UniProt ID
- P0DTC3
- Gene Symbol
-
- 3a
- Organism
- Severe acute respiratory syndrome coronavirus 2
Annotation
- Keyword
-
- 3D-structure
- Activation of host autophagy by virus
- Glycoprotein
- Host cell membrane
- Host cytoplasm
- Host endoplasmic reticulum
- Host endosome
- Host lysosome
- Reference proteome
- Secreted
- Transmembrane helix
- Viral ion channel
- Virion
- Gene Ontology (GO)
| GO Term |
|---|
| induction by virus of host reticulophagy |
| induction by virus of host autophagy |
| inorganic cation transmembrane transport |
| GO Term |
|---|
| molecular function activator activity |
| monoatomic ion channel activity |
| identical protein binding |
Sequence
MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Attachment and Entry | Homo sapiens |
| Induction of Cell-Cell Fusion | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| SARS-CoV-2 modulates autophagy | Homo sapiens |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | Homo sapiens |
| Translation of Structural Proteins | Homo sapiens |
| Virion Assembly and Release | Homo sapiens |
