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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hepatic triacylglycerol lipase
Summary
- UniProt ID
- P11150
- Gene Symbol
-
- LIPC
- HTGL
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P11150
- SwissLipids
- The Human Metabolome Database
- HMDBP00226
Annotation
- Keyword
-
- Direct protein sequencing
- Disease variant
- Glycoprotein
- HDL
- Heparin-binding
- Hydrolase
- Lipid degradation
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| chylomicron remnant clearance |
| triglyceride homeostasis |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| endoplasmic reticulum lumen |
| high-density lipoprotein particle |
| GO Term |
|---|
| phosphatidyl phospholipase B activity |
Sequence
MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly of active LPL and LIPC lipase complexes | Homo sapiens |
| Chylomicron clearance | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:6713 | cerebrovascular disease | |
| DOID:784 | chronic kidney disease | |
| DOID:8543 | Hodgkin's lymphoma, lymphocytic-histiocytic predominance | |
| DOID:8567 | Hodgkin's lymphoma | |
| DOID:8628 | Hodgkin's lymphoma, lymphocytic depletion | |
| DOID:8651 | Hodgkin's granuloma | |
| DOID:8654 | Hodgkin's lymphoma, mixed cellularity | |
| DOID:9080 | macroglobulinemia | |
| DOID:9256 | colorectal cancer | |
| DOID:9351 | diabetes mellitus |
