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Lipoprotein lipase

Summary

UniProt ID

P11152

Gene Symbol

Gene ID

16956

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003346
GlyGen: P11152
PubChem: P11152
RaftProt: P11152
Re-Glyco: P11152

Annotation

Keyword

Calcium
Cell membrane
Chylomicron
Disulfide bond
Extracellular matrix
Glycoprotein
Heparin-binding
Hydrolase
Lipid degradation
Metal-binding
Nitration
Reference proteome
Signal
VLDL

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
catalytic complex
extracellular space
plasma membrane
chylomicron
cell surface
very-low-density lipoprotein particle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
fatty acid biosynthetic process
triglyceride catabolic process
positive regulation of interleukin-1 beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
cholesterol homeostasis
triglyceride homeostasis
positive regulation of adipose tissue development
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage

Displaying entries **1 - 10** of 11 in total

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GO Term
lipoprotein lipase activity
triglyceride lipase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
phospholipase A1 activity
phosphatidylserine 1-acylhydrolase activity
lipoprotein particle binding
signaling receptor binding
calcium ion binding

Annotation information from UniProt.

Sequence

MESKALLLVVLGVWLQSLTAFRGGVAAADAGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTEDGKQHNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMMKLKWISDSYFSWPDWWSSPSFVIERIRVKAGETQKKVIFCAREKVSHLQKGKDSAVFVKCHDKSLKKSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
70	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
386	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Assembly of active LPL and LIPC lipase complexes	Mus musculus
Chylomicron remodeling	Mus musculus
Retinoid metabolism and transport	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14118	familial lipoprotein lipase deficiency	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements