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E3 SUMO-protein ligase EGR2

Summary

UniProt ID

P11161

Gene Symbol

EGR2
KROX20

Organism

Homo sapiens (human)

External Links

GlyGen: P11161
PubChem: P11161
The O-GlcNAc Database: P11161
O-GlcNAcAtlas: P11161

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Charcot-Marie-Tooth disease
DNA-binding
Dejerine-Sottas syndrome
Disease variant
Neurodegeneration
Nucleus
Reference proteome
Repeat
Transcription regulation
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

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GO Term
brain segmentation
fat cell differentiation
cellular response to organic substance
facial nerve structural organization
rhombomere 3 structural organization
rhombomere 3 formation
rhombomere 5 structural organization
rhombomere 5 formation
regulation of neuronal synaptic plasticity
regulation of transcription by RNA polymerase II

Displaying **all 5** entries
GO Term
nucleoplasm
chromatin
nucleus
cytoplasm
intracellular membrane-bounded organelle

Displaying entries **1 - 10** of 13 in total

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GO Term
RNA polymerase II-specific DNA-binding transcription factor binding
SUMO ligase activity
ubiquitin protein ligase binding
transcription cis-regulatory region binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 14** of 14 in total

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Position	GlyTouCan ID	Source
289	G49108TO	GlyGen The O-GlcNAc Database
299	G49108TO	GlyGen The O-GlcNAc Database
382	G49108TO	GlyGen The O-GlcNAc Database
387	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Activation of anterior HOX genes in hindbrain development during early embryogenesis	Homo sapiens
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Homo sapiens
NGF-stimulated transcription	Homo sapiens
Transcriptional regulation of white adipocyte differentiation	Homo sapiens