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MIRAGE
Mannose-binding protein C
Summary
- UniProt ID
- P11226
- Gene Symbol
-
- COLEC1
- MBL
- MBL2
- Gene ID
- 4153
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P11226
- PubChem
- P11226
- The Human Metabolome Database
- HMDBP02647
- Re-Glyco
- P11226
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Coiled coil
- Collagen
- Complement activation lectin pathway
- Complement pathway
- Direct protein sequencing
- Disulfide bond
- Hydroxylation
- Mannose-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| collagen trimer |
| extracellular space |
| external side of plasma membrane |
| cell surface |
| multivesicular body |
| serine-type endopeptidase complex |
| GO Term |
|---|
| signaling receptor binding |
| mannose binding |
| identical protein binding |
| calcium-dependent protein binding |
Sequence
MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 171 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:104 | bacterial infectious disease | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10754 | otitis media | |
| DOID:10887 | lepromatous leprosy | |
| DOID:11162 | respiratory failure | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11650 | bronchopulmonary dysplasia | |
| DOID:12177 | common variable immunodeficiency | |
| DOID:12306 | vitiligo | |
| DOID:12554 | hemolytic-uremic syndrome |
