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Glucose-6-phosphate 1-dehydrogenase

Summary

UniProt ID

P11413

Gene Symbol

G6PD

Organism

Homo sapiens (human)

External Links

GlyGen: P11413
PubChem: P11413
The Human Metabolome Database: HMDBP00328
The O-GlcNAc Database: P11413
RaftProt: P11413
O-GlcNAcAtlas: P11413

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Disease variant
Glucose metabolism
Hereditary hemolytic anemia
Hydroxylation
Membrane
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 10** of 23 in total

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GO Term
glucose metabolic process
lipid metabolic process
response to organic cyclic compound
substantia nigra development
cellular response to oxidative stress
erythrocyte maturation
regulation of neuron apoptotic process
negative regulation of cell growth involved in cardiac muscle cell development
negative regulation of reactive oxygen species metabolic process
response to food

Displaying **all 7** entries
GO Term
cytosol
cytoplasm
membrane
intracellular membrane-bounded organelle
extracellular exosome
cytoplasmic side of plasma membrane
centriolar satellite

Displaying **all 5** entries
GO Term
glucose binding
NADP binding
identical protein binding
protein homodimerization activity
glucose-6-phosphate dehydrogenase activity

Annotation information from UniProt.

Sequence

MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites