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Heat shock protein HSP 90-beta

Summary

UniProt ID

P11499

Gene Symbol

Hsp84
Hsp84-1
Hsp90ab1
Hspc3
Hspcb

Gene ID

15516

Organism

Mus musculus (house mouse)

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cell membrane
Chaperone
Cytoplasm
Direct protein sequencing
Glycoprotein
Methylation
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
Secreted
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
dynein axonemal particle
extracellular region
nucleus
cytoplasm
mitochondrion
plasma membrane
protein-containing complex
melanosome
neuronal cell body
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
positive regulation of protein localization to cell surface
protein folding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular response to interleukin-4
supramolecular fiber organization
negative regulation of proteasomal protein catabolic process
telomerase holoenzyme complex assembly
virion attachment to host cell
positive regulation of transforming growth factor beta receptor signaling pathway
cellular response to heat

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GO Term
unfolded protein binding
nitric-oxide synthase regulator activity
ATP-dependent protein binding
receptor ligand inhibitor activity
double-stranded RNA binding
ATP binding
ATP hydrolysis activity
kinase binding
protein kinase binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
46				GlycoProtDB
283			G80920RR	GlyGen
389			G80920RR	GlyGen
434	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
452	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
462			G49108TO	The O-GlcNAc Database
614			G02815KT	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Mus musculus
Attenuation phase	Mus musculus
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Mus musculus
ESR-mediated signaling	Mus musculus
Estrogen-dependent gene expression	Mus musculus
HSF1 activation	Mus musculus
HSF1-dependent transactivation	Mus musculus
HSP90 chaperone cycle for SHRs	Mus musculus
Neutrophil degranulation	Mus musculus
RHOBTB2 GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements