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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibronectin
Summary
- UniProt ID
- P11722
- Gene Symbol
-
- FN1
- Organism
- Gallus gallus (chicken)
External Links
- PubChem
- P11722
Annotation
- Keyword
-
- Acute phase
- Alternative splicing
- Cell adhesion
- Cell shape
- DNA-binding
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Phosphoprotein
- Pyrrolidone carboxylic acid
- Reference proteome
- Repeat
- Signal
- Sulfation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| endoplasmic reticulum-Golgi intermediate compartment |
| cell surface |
| apical plasma membrane |
| perinuclear region of cytoplasm |
| fibrinogen complex |
| basement membrane |
| extracellular space |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| heparin binding |
| protease binding |
| DNA binding |
| integrin binding |
| peptidase activator activity |
| identical protein binding |
| proteoglycan binding |
Sequence
MPGRGGLRLALLALCLGAAAAGGGDGQRRGGKNRRQAQTASVPQATPAQGKQTCFDNGRYYQINQQWERIYLGNTLVCTCYGGSRGFNCESKPEPEETCFDKYTGSTYRVGETYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGKSYKIGDTWRRPHETGGYLLECVCLGNGKGEWTCKPLAERCYDNTAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTKTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSLHTTSTGSGSPSFTNVQTALYQPQPQQPQPQPHGHCVTDNGVVYSLGMQWLKTQGSQQMLCTCLGNGVSCQEIAVTQTYGGNSDGEACVLPFTYNGRTFYSCTTEGRTDGHLWCSTTSNFEQDRRYSFCTEQNVLVQTRGGNSNGALCHFPFLYNNRNYTDCTSEGRRDNMKWCGTTENYDADQKFGFCPMAAHEEICTTNDGIMYRVGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDGITYDVNQTFHKRHDEGHMLNCTCFGQGRGRWKCDPVDQCQDSETRTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQAYAGATGPVQVIITESTNQPNSHPIQWNAPKTSHISKYILRWRPKISGRHWKEATIPGHLNSYTISGLKPGVVYEGQLISVQQHGPKEVTRFDFTTTSTTAVTSNTVSGETTLLPPMVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEEGEQNLILSTSQTTAPDAPPEHSVESVDDTSIVISWSRPQAPITGYRIVYTPSVEGSSTELNLPDTATSVTLSDLMPGVQYNISIYAVEEHQESTPVFIQQETTGVPRTDEVPSPKDLQFVEVSDVKVTIMWTPPQSQVSGYRVEAIPVNRPGQHGQRLPITRSSFAEVVDLLPGTTYLFKIFAVSHGRESKPLTGEQTTKLDAPTNLRFINTTEHSVLVLWTRPRAIISGYRLTAGPTRGGQPRTYNVGPSATKYLLRNLQPGTEYTVYLVAVKEDLQSARETGVFTTYQPVGSVPPFNTEVTETSIVITWTPAPRIGFKLGVRPSQGGEAPREVISDSGSIVISGLTPGVEYTYSLTVLMDGQERETPIIRRVTTPLSPPTNLRLEPNPDTGILIVSWDRSTTPGISGYRVTTAPTNGQQGSTLEEVVGADQTSCTFENLNPGVEYNVSVYAVKDDQESIPISKTITQEVPQLTDLSFVDITDSSIGLRWTPLNASTIIGYRITVVAAGESVPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNVGPDTMRVTWTAPTSIVLSSFLVRYSPVKKEEDVAELTISPSDNVVVLTNLLPGTEYLVRVYSVAEQHESAPLSGIQKTGLDSPTGLDFSDITANSFTVHWIAPRATITGYKIRHHPEHGVGRPKEDRVPPSRNSITLTNLLPGTEYVVSIIAVNGREESVPLVGQQTTVSDVPRDLEVNPTSPTSLEISWDAPAVTVRYYRITYGETGGSSPVQEFTVPGTMSRATITGLKPGVDYTITVYAVTGRGDSPASSKPVTVTYKTEIDTPSQMQVTDVQDNSISIRWLPSSSPVTGYRVTAVPKKGHGPTKTKNVPPDQTQVTIEGLQPTVEYMVSVYAQNQNGESLPLVETAVTNIDRPKGLTFTEVDVDSIKIAWESPQGQVTRYRVTYSSPEDGIHELLPAPGGEEDTAELHGLRPGSEYTINIVAIYDDMESLPLTGTQSTAIPPPTNLKFTQVTPTSLTVNWNAPNVRLTGYRVRVNPKEKTGPMKEINLSPDSTSAVVSGLMVATKYEVSVYALKDSLTSRPAQGVVTTLENVSPPRRARVTDATETTITITWRTKTETITGFQIDAIPAASGQNPIQRTISPDVRTYTITGLQPGNDYKIYLYTLNENARSSPVVIDASTAIDAPSNLRFLTTTTNSLLASWQPPRAKITGYIIRYDKPGSPAKELLPRPRPGTTEATITGLEPGTEYTIYIIAVKNNQKSEPLVGRKRTDDLPTLITGPHPNQPDMLDVPSVDEGTPYLTNNRYDNGNGIQLPGTSGHPQTIGHQGQQVFFEEHGYRRPVPTTATPLRPGSRRQPPNVDEAIEIPGYQVPIIVVPSYPHSREPRRNDTTGQEALSQTTISWRPLLESTEYIISCQPVSQDEDTLQFRVPGTSSSATLTGLTRGATYNIIVEALKDHRRQKVLEEVVTVGNTVSEGLNQPADDTCYDTYTGSFYSIGEEWERLSETGFKLWCQCLGFGSGHFRCDSSKWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCEPHETTCYDDGKMYQVGEQWQKEYFGAICSCTCYGGQQGWRCDNCRRPSVEVAPEGSAGHTYPQFTQRYHQATNTNVNCPIECFMPLDVQADTQHPRGK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 435 | N-linked (GlcNAc...) asparagine |
|
||
| 533 | N-linked (GlcNAc...) asparagine |
|
||
| 547 | N-linked (GlcNAc...) asparagine |
|
||
| 881 | N-linked (GlcNAc...) asparagine |
|
||
| 1011 | N-linked (GlcNAc...) asparagine |
|
||
| 1248 | N-linked (GlcNAc...) asparagine |
|
||
| 1295 | N-linked (GlcNAc...) asparagine |
|
||
| 2204 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fibronectin matrix formation | Gallus gallus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Gallus gallus |
| Integrin cell surface interactions | Gallus gallus |
| Integrin signaling | Gallus gallus |
| MAP2K and MAPK activation | Gallus gallus |
| Platelet degranulation | Gallus gallus |
| Post-translational protein phosphorylation | Gallus gallus |
| Regulation of IGF Activity by IGFBP | Gallus gallus |
| p130Cas linkage to MAPK signaling for integrins | Gallus gallus |
