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Pyruvate kinase PKM

Summary

UniProt ID

P11980

Gene Symbol

Pkm
Pkm2
Pykm

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P11980
PubChem: P11980
The O-GlcNAc Database: P11980
RaftProt: P11980

Annotation

Keyword

ATP-binding
Acetylation
Allosteric enzyme
Alternative splicing
Cytoplasm
Direct protein sequencing
Glycolysis
Hydroxylation
Isopeptide bond
Kinase
Magnesium
Metal-binding
Methylation
Nucleus
Phosphoprotein
Potassium
Pyruvate
Reference proteome
S-nitrosylation
Translation regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 21 in total

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GO Term
liver development
glucose metabolic process
response to gravity
response to organic substance
programmed cell death
phosphorylation
cellular response to insulin stimulus
animal organ regeneration
response to insulin
skeletal muscle tissue regeneration

Displaying **all 6** entries
GO Term
pyruvate kinase complex
nucleus
cytoplasm
cilium
cytosol
rough endoplasmic reticulum

Displaying **all 10** entries
GO Term
potassium ion binding
identical protein binding
protein dimerization activity
pyruvate kinase activity
thyroid hormone binding
magnesium ion binding
mRNA binding
ADP binding
protein tyrosine kinase activity
ATP binding

Annotation information from UniProt.

Sequence

MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites