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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Metalloproteinase inhibitor 1
Summary
- UniProt ID
- P12032
- Gene Symbol
-
- Timp1
- Timp
- Timp-1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003369
- PubChem
- P12032
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Growth factor
- Metal-binding
- Metalloprotease inhibitor
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| connective tissue replacement involved in inflammatory response wound healing |
| negative regulation of endopeptidase activity |
| negative regulation of membrane protein ectodomain proteolysis |
| GO Term |
|---|
| extracellular matrix |
| basement membrane |
| extracellular space |
| GO Term |
|---|
| zinc ion binding |
| protease binding |
| cytokine activity |
| growth factor activity |
| metalloendopeptidase inhibitor activity |
Sequence
MMAPFASLASGILLLLSLIASSKACSCAPPHPQTAFCNSDLVIRAKFMGSPEINETTLYQRYKIKMTKMLKGFKAVGNAADIRYAYTPVMESLCGYAHKSQNRSEEFLITGRLRNGNLHISACSFLVPWRTLSPAQQRAFSKTYSAGCGVCTVFPCLSIPCKLESDTHCLWTDQVLVGSEDYQSRHFACLPRNPGLCTWRSLGAR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 54 | N-linked (GlcNAc...) asparagine |
|
||
| 102 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Mus musculus |
| Platelet degranulation | Mus musculus |
| Post-translational protein phosphorylation | Mus musculus |
| Regulation of IGF Activity by IGFBP | Mus musculus |
| TGFBR3 PTM regulation | Mus musculus |
