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Neuronal acetylcholine receptor subunit beta-2

Summary

UniProt ID

P12390

Gene Symbol

Chrnb2
Acrb2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P12390

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 49 in total

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GO Term
neuronal action potential
central nervous system neuron axonogenesis
response to cocaine
response to ethanol
membrane depolarization
calcium ion transport
associative learning
central nervous system projection neuron axonogenesis
positive regulation of synaptic transmission, dopaminergic
response to nicotine

Displaying entries **1 - 10** of 12 in total

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GO Term
presynaptic membrane
plasma membrane raft
acetylcholine-gated channel complex
cholinergic synapse
postsynaptic specialization membrane
external side of plasma membrane
plasma membrane
protein-containing complex
neuron projection
synapse

Displaying **all 7** entries
GO Term
acetylcholine binding
quaternary ammonium group binding
heterocyclic compound binding
protein-containing complex binding
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine receptor activity
acetylcholine-gated monoatomic cation-selective channel activity

Annotation information from UniProt.

Sequence

MAGHSNSMALFSFSLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQRLRLRRRQREREGAGALFFREGPAADPCTCFVNPASVQGLAGAFRAEPTAAGPGRSVGPCSCGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTVGMFLQPLFQNYTATTFLHPDHSAPSSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
50	N-linked (GlcNAc...) asparagine			UniProt
167	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Highly calcium permeable nicotinic acetylcholine receptors	Rattus norvegicus
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Rattus norvegicus
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Rattus norvegicus