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DNA (cytosine-5)-methyltransferase 1

Summary

UniProt ID

P13864

Gene Symbol

Dnmt
Dnmt1
Met1
Uim

Gene ID

13433

Organism

Mus musculus (house mouse)

External Links

GlyGen: P13864
PubChem: P13864
O-GlcNAcAtlas: P13864
Re-Glyco: P13864

Annotation

Keyword

3D-structure
Acetylation
Activator
Allosteric enzyme
Alternative splicing
Chromatin regulator
Cytoplasm
DNA-binding
Direct protein sequencing
Isopeptide bond
Methylation
Methyltransferase
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
heterochromatin
nucleus
cytoplasm
nucleoplasm
replication fork
pericentric heterochromatin
germ cell nucleus
female germ cell nucleus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

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GO Term
cellular response to bisphenol A
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
negative regulation of transcription by RNA polymerase II
DNA-templated transcription
methylation
negative regulation of DNA-templated transcription
cellular response to amino acid stimulus
positive regulation of vascular associated smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell apoptotic process
DNA methylation-dependent heterochromatin formation

Displaying entries **1 - 10** of 13 in total

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GO Term
DNA binding
RNA binding
methyltransferase activity
promoter-specific chromatin binding
DNA (cytosine-5-)-methyltransferase activity
lncRNA binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates
chromatin binding
zinc ion binding

Annotation information from UniProt.

Sequence

MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVREKLNLLHEFLQTEIKSQLCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGTHTLTQKANGCPANGSRPTWRAEMADSNRSPRSRPKPRGPRRSKSDSDTLSVETSPSSVATRRTTRQTTITAHFTKGPTKRKPKEESEEGNSAESAAEERDQDKKRRVVDTESGAAAAVEKLEEVTAGTQLGPEEPCEQEDDNRSLRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSRPRSQPRDPAAKRRPKEAEPEQVAPETPEDRDEDEREEKRRKTTRKKLESHTVPVQSRSERKAAQSKSVIPKINSPKCPECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSIYDSTSTWFDTYEDSPMHRFTSFSVYCSRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEKVLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETTVPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQRRATRRVMGATKEKDKAPTKATTTKLVYQIFDTFFSEQIEKYDKEDKENAMKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADDDVSEMPSPKKLHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPVKRPKKDPVNETLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGKGKGKGKGKHQVSEPKEPEAAIKLPKLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIQNGASNSEIPYNGEPLSWFQRQLRGSHYQPILRDHICKDMSPLVAARMRHIPLFPGSDWRDLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDSYRFFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites