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DNA (cytosine-5)-methyltransferase 1

Summary

UniProt ID

P13864

Gene Symbol

Dnmt1
Dnmt
Met1
Uim

Organism

Mus musculus (house mouse)

External Links

GlyGen: P13864
PubChem: P13864
O-GlcNAcAtlas: P13864

Annotation

Keyword

3D-structure
Acetylation
Activator
Allosteric enzyme
Alternative splicing
Chromatin regulator
Cytoplasm
DNA-binding
Direct protein sequencing
Isopeptide bond
Methylation
Methyltransferase
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

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GO Term
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
regulation of cell population proliferation
cellular response to amino acid stimulus
positive regulation of vascular associated smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell apoptotic process
post-fertilization epigenetic regulation of gene expression
negative regulation of gene expression via CpG island methylation
negative regulation of transcription by RNA polymerase II

Displaying **all 9** entries
GO Term
heterochromatin
female germ cell nucleus
nucleus
protein-containing complex
germ cell nucleus
cytoplasm
nucleoplasm
pericentric heterochromatin
replication fork

Displaying entries **1 - 10** of 15 in total

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GO Term
promoter-specific chromatin binding
protein domain specific binding
nuclear estrogen receptor binding
methyltransferase activity
DNA (cytosine-5-)-methyltransferase activity
DNA-methyltransferase activity
zinc ion binding
methyl-CpG binding
histone deacetylase binding
lncRNA binding

Annotation information from UniProt.

Sequence

MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVREKLNLLHEFLQTEIKSQLCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGTHTLTQKANGCPANGSRPTWRAEMADSNRSPRSRPKPRGPRRSKSDSDTLSVETSPSSVATRRTTRQTTITAHFTKGPTKRKPKEESEEGNSAESAAEERDQDKKRRVVDTESGAAAAVEKLEEVTAGTQLGPEEPCEQEDDNRSLRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSRPRSQPRDPAAKRRPKEAEPEQVAPETPEDRDEDEREEKRRKTTRKKLESHTVPVQSRSERKAAQSKSVIPKINSPKCPECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSIYDSTSTWFDTYEDSPMHRFTSFSVYCSRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEKVLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETTVPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQRRATRRVMGATKEKDKAPTKATTTKLVYQIFDTFFSEQIEKYDKEDKENAMKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADDDVSEMPSPKKLHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPVKRPKKDPVNETLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGKGKGKGKGKHQVSEPKEPEAAIKLPKLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIQNGASNSEIPYNGEPLSWFQRQLRGSHYQPILRDHICKDMSPLVAARMRHIPLFPGSDWRDLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDSYRFFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites