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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glucosidase 2 subunit beta
Summary
- UniProt ID
- P14314
- Gene Symbol
-
- PRKCSH
- G19P1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011528
- GlyConnect
- GlyGen
- P14314
- PubChem
- P14314
- The Human Metabolome Database
- HMDBP01163
- The O-GlcNAc Database
- P14314
- RaftProt
- P14314
- O-GlcNAcAtlas
- P14314
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| liver development |
| intracellular signal transduction |
| N-glycan processing |
| GO Term |
|---|
| glucosidase II complex |
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
| intracellular membrane-bounded organelle |
| GO Term |
|---|
| calcium ion binding |
| phosphoprotein binding |
| transmembrane transporter binding |
| protein kinase C binding |
Sequence
MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 72 | N-linked (GlcNAc...) asparagine | |||
| 79 |
|
|
||
| 90 |
|
|
||
| 134 |
|
|||
| 263 |
|
|||
| 280 |
|
|||
| 282 |
|
|||
| 287 |
|
|||
| 293 |
|
|||
| 298 |
|
G80920RR
G39188ZX
G57321FI
G43417UB
G49108TO
G58001LT
G29068FM
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Advanced glycosylation endproduct receptor signaling | Homo sapiens |
| Calnexin/calreticulin cycle | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050770 | polycystic liver disease | |
| DOID:0050778 | Meckel syndrome | |
| DOID:0050990 | episodic ataxia type 2 | |
| DOID:0050997 | cerebellar ataxia, mental retardation and dysequlibrium syndrome | |
| DOID:0060178 | familial hemiplegic migraine | |
| DOID:0060262 | gallbladder disease | |
| DOID:0110741 | type 1 diabetes mellitus 2 | |
| DOID:0110742 | type 1 diabetes mellitus 3 | |
| DOID:0110743 | type 1 diabetes mellitus 4 | |
| DOID:0110744 | type 1 diabetes mellitus 5 |
