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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Farnesyl pyrophosphate synthase
Summary
- UniProt ID
- P14324
- Gene Symbol
-
- FDPS
- FPS
- KIAA1293
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cholesterol biosynthesis
- Cytoplasm
- Disease variant
- Host-virus interaction
- Hydroxylation
- Isoprene biosynthesis
- Magnesium
- Metal-binding
- Reference proteome
- Transferase
- Gene Ontology (GO)
| GO Term |
|---|
| cholesterol biosynthetic process |
| farnesyl diphosphate biosynthetic process |
| geranyl diphosphate biosynthetic process |
| GO Term |
|---|
| cytoplasm |
| cytosol |
| nucleoplasm |
| GO Term |
|---|
| RNA binding |
| metal ion binding |
| dimethylallyltranstransferase activity |
| geranyltranstransferase activity |
Sequence
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 4 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| Cholesterol biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1909 | melanoma | |
| DOID:1936 | atherosclerosis | |
| DOID:2030 | anxiety disorder | |
| DOID:219 | colon cancer | |
| DOID:2326 | gastroenteritis | |
| DOID:2348 | arteriosclerotic cardiovascular disease | |
| DOID:2349 | arteriosclerosis | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2848 | obsolete melancholia | |
| DOID:3068 | glioblastoma |
