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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Aldo-keto reductase family 1 member B1
Summary
- UniProt ID
- P15121
- Gene Symbol
-
- AKR1B1
- ALDR1
- ALR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Direct protein sequencing
- Lipid metabolism
- NADP
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| epithelial cell maturation |
| renal water homeostasis |
| cellular hyperosmotic salinity response |
| GO Term |
|---|
| extracellular space |
| nucleoplasm |
| extracellular exosome |
| cytosol |
Sequence
MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 160 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fructose biosynthesis | Homo sapiens |
| Pregnenolone biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050426 | Stevens-Johnson syndrome | |
| DOID:0050580 | hereditary lymphedema | |
| DOID:0050757 | deafness-dystonia-optic neuronopathy syndrome | |
| DOID:0060185 | Clostridium difficile colitis | |
| DOID:0060597 | atypical chronic myeloid leukemia, BCR-ABL1 negative | |
| DOID:0070210 | hereditary lymphedema IA | |
| DOID:0070212 | hereditary lymphedema I | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080156 | X-linked adrenal hypoplasia congenita | |
| DOID:0080199 | colorectal carcinoma |
